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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIAM2
All Species:
13.64
Human Site:
S1598
Identified Species:
42.86
UniProt:
Q8IVF5
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IVF5
NP_001010927.1
1701
190113
S1598
Q
F
Q
R
L
R
I
S
E
D
P
D
V
H
P
Chimpanzee
Pan troglodytes
XP_527545
1701
190152
S1598
Q
F
Q
R
L
R
I
S
E
D
P
D
V
H
P
Rhesus Macaque
Macaca mulatta
XP_001098107
1591
177452
T1502
E
Q
D
D
I
K
E
T
D
I
L
S
D
D
D
Dog
Lupus familis
XP_541162
1487
166908
E1397
D
P
D
A
N
A
A
E
Q
Q
P
S
T
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPF3
1715
192548
S1619
Q
F
Q
R
L
K
I
S
E
E
S
D
V
H
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419687
1705
192295
S1601
Q
F
Q
R
L
K
I
S
E
E
P
S
T
D
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91620
2061
229913
P1937
Q
G
H
A
H
A
H
P
H
P
H
P
H
P
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788791
1150
129570
A1061
S
G
V
P
N
S
P
A
S
A
G
V
P
P
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
38.9
78.3
N.A.
83.7
N.A.
N.A.
N.A.
77.9
N.A.
N.A.
N.A.
26.4
N.A.
N.A.
24.6
Protein Similarity:
100
99.4
56.5
81.5
N.A.
89.1
N.A.
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
41.8
N.A.
N.A.
39.8
P-Site Identity:
100
100
0
6.6
N.A.
80
N.A.
N.A.
N.A.
60
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
33.3
13.3
N.A.
93.3
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
25
0
25
13
13
0
13
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
25
13
0
0
0
0
13
25
0
38
13
25
13
% D
% Glu:
13
0
0
0
0
0
13
13
50
25
0
0
0
13
0
% E
% Phe:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
13
% F
% Gly:
0
25
0
0
0
0
0
0
0
0
13
0
0
0
13
% G
% His:
0
0
13
0
13
0
13
0
13
0
13
0
13
38
0
% H
% Ile:
0
0
0
0
13
0
50
0
0
13
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
38
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
50
0
0
0
0
0
13
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
25
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
13
0
13
0
0
13
13
0
13
50
13
13
25
38
% P
% Gln:
63
13
50
0
0
0
0
0
13
13
0
0
0
0
0
% Q
% Arg:
0
0
0
50
0
25
0
0
0
0
0
0
0
0
13
% R
% Ser:
13
0
0
0
0
13
0
50
13
0
13
38
0
0
13
% S
% Thr:
0
0
0
0
0
0
0
13
0
0
0
0
25
0
0
% T
% Val:
0
0
13
0
0
0
0
0
0
0
0
13
38
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _